Archive for April, 2009

Ileus

Monday, April 13th, 2009

Definition
Is a partial or total blockage of the intestine that causes a failure to evacuate his bowel contents.

Causes, incidence and risk factors

Occlusion of the intestine may be due to:

* A mechanical cause, which simply means that there is something in the road.
* Ileus, a condition in which the bowel is not functioning correctly, but there is a structural problem.

The paralytic ileus, also called seudoobstrucción is a major cause of intestinal obstruction in infants and children. The causes of paralytic ileus may include the following:

* Alterations chemical or electrolytic minerals, such as a decrease in potassium levels
* Complications of abdominal surgery
* Decreased blood supply to the abdominal area (ischemia of the mesenteric artery)
* Damage to the abdominal blood supply
* Intraperitoneal Infection
* Kidney disease or thoracic
* Use of certain medications, especially narcotics

In older children, the paralytic ileus may be due to food poisoning, viruses or bacteria (gastroenteritis) is sometimes associated with secondary peritonitis and appendicitis.

The causes of mechanical intestinal obstruction may include:

* Abnormal tissue growth
* Adhesions or scar tissue that forms after surgery
* Foreign bodies (ingested materials that obstruct the intestines)
Gallstones *
* Hernias
* Holding fecal (stool)
Intussusception *
* Tumors blocking the intestines
* Volvulus (twisting of the intestine)

Symptoms

* Abdominal distention
* Abdominal fullness by gas
* Abdominal pain and cramping
* Bad breath
* Constipation
* Diarrhea
* Vomiting

Anti-HIV treatment

Friday, April 3rd, 2009

The anti-HIV treatment began to change radically with the introduction of the first protease inhibitor in 1995. Regimens combining protease inhibitors and reverse transcriptase inhibitors are the basis of (HAART) therapy for high efficiency, and which have improved survival and reduced survival of AIDS-related illnesses. Roche has also developed a reverse transcriptase inhibitor, an antiretroviral that has shown significantly prolong survival and reduce the onset of opportunistic infections. Cytomegalovirus Cytomegalovirus (CMV) infection is a common, normally inactive in individuals with healthy immune systems. The virus can become active in people with weakened immune systems, and whether it affects the eye, left untreated, can cause blindness. The effectiveness of HAART has reduced the number of people developing AIDS and thus the incidence of CMV infection. Despite this reduction, the commitment of Roche to people living with HIV and AIDS out for the future development of new treatments. In addition, Roche Diagnostics also offers a PCR test to measure the viral load of CMV, the sample of the Amplicor Monitor CMV.
Roche has developed a reverse transcriptase inhibitor, zalcitabine, a protease inhibitor, saquinavir and commercializes the protease inhibitor used in the world, nelfinavir. He has also developed standard ganciclovir treatment of an opportunistic infection common in people with advanced HIV infection, CMV retinitis (CMV).